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Design of Pilot-scale Extraction Platform in Biotechnology Engineering

1. Microfiltration System (BNCM1-3-M) 



Product Specifications: 

◆ Minimum circulation volume: 12L; 

◆ Material tank: 48L; 

◆ Work pressure: 0 - 0.4 MPa; 

◆ Allowable operating temperature: 5 - 80℃; 

◆ Pump power: 1.5KW; 

◆ pH range of application: 0 - 14; 

◆ Filtration rate: 20 - 100 L/H; 

◆ Single-core filtration area: 0.286 square meters; 

◆ Membrane element: Three 0.5um ceramic membrane elements; 

◆ Flow channel specification size: 19 channels × 4mm; 

◆ Control method: Manual control; 

◆ Power demand: Three-phase / 220V / 50Hz (It is recommended to reserve according to the factory standards); 

◆ Equipment dimensions: 1350 (length) × 900 (width) × 1950 (height) mm; 

Product Process and Feature Introduction: 

1. Integrated equipment structure, equipped with rollers, and fast-installation towers at the inlet and outlet. 

2. The system is equipped with an automatic overpressure protection function. In case of overpressure, it will automatically shut down. It also has an automatic overtemperature protection feature. If the temperature exceeds the limit, it will automatically stop. 

3. It adopts a three-membrane shell parallel structure. Through the valve switching mechanism, any single membrane element can be used, or multiple membrane elements can be used simultaneously. 

4. All stainless steel welding is carried out using automatic argon gas protection, with single-sided welding and double-sided forming. The inner and outer surfaces of the pipeline have excellent quality. The operation is simple, the environment is clean and hygienic, and it is safe and reliable. 

5. Equipped with an automatic backwashing system, with the program set to automatically perform backwashing. 

6. Equipped with a heat exchanger, it can cool or heat the materials. 

Basic configuration: 

One multi-stage vertical centrifugal pump, three SUS304 ceramic membrane modules, three ceramic membrane elements, two flow meters, one pressure gauge, one temperature sensor, one pressure sensor, one pressure regulating valve, one jacketed material tank, one heat exchanger, one backwashing system; equipment brackets, interlocking couplings, various pipes and their connecting components; one variable frequency start-up system. 

Optional model with membrane elements: 

• Ceramic microfiltration membrane elements: 50nm, 100nm, 200nm, 400nm, 600nm, 800nm, 1um, 1.2um, 1.5um, 2um 

Ceramic ultrafiltration membrane elements: 30nm (200KD), 20nm (150KD), 12nm (100KD), 10nm (20KD), 5nm (8000D), 3nm (2000D) 





II. Ultrafiltration System (BNCM1-4-M) 



Product Specifications: 

◆ Minimum circulation volume: 12L; 

◆ Material tank: 48L; 

◆ Work pressure: 0 - 0.4 MPa; 

◆ Allowable operating temperature: 5 - 80℃; 

◆ Pump power: 1.5KW; 

◆ pH range of application: 0 - 14; 

◆ Filtration rate: 20 - 100 L/H; 

◆ Single-core filtration area: 0.286 square meters; 

◆ Flow channel specification size: 19 channels × 4mm; 

◆ Control method: Manual control; 

◆ Power demand: Three-phase / 220V / 50Hz (It is recommended to reserve according to the factory standards); 

◆ Membrane elements: Two 0.05μm ceramic membrane elements, one 100,000D ceramic membrane element, and one 10,000D ceramic membrane element; 

◆ Equipment dimensions: 1350 (length) × 900 (width) × 1950 (height) mm; 

Product Features: 

1. Integrated equipment structure, equipped with rollers, and fast-installation towers at the inlet and outlet. 

2. The system is equipped with an automatic overpressure protection function. In case of overpressure, it will automatically shut down. It also has an automatic overtemperature protection feature. If the temperature exceeds the limit, it will automatically stop. 

3. It adopts a four-membrane parallel structure. Through the valve switching mechanism, any single membrane element can be used, or multiple membrane elements can be used simultaneously. 

4. All stainless steel welding is carried out using automatic argon gas protection, with single-sided welding and double-sided forming. The inner and outer surfaces of the pipeline have excellent quality. The operation is simple, the environment is clean and hygienic, and it is safe and reliable. 

5. Equipped with an automatic backwashing system, with the program set to automatically perform backwashing. 

6. Equipped with a heat exchanger, it can cool or heat the materials. 

Basic configuration: 

One multi-stage vertical centrifugal pump, four SUS304 ceramic membrane modules, and four ceramic membrane elements; one pressure gauge, one temperature sensor, one pressure sensor, two flow meters, one pressure regulating valve, one jacketed material tank; one heat exchanger; one backwashing system; several equipment supports, interlocking couplings, pipelines and their connecting components; one basic electrical control cabinet and one variable frequency start-up system. 

Optional model with membrane elements: 

• Ceramic microfiltration membrane elements: 50nm, 100nm, 200nm, 400nm, 600nm, 800nm, 1um, 1.2um, 1.5um, 2um 

• Ceramic ultrafiltration membrane elements: 30nm (200KD), 20nm (150KD), 12nm (100KD), 10nm (20KD), 5nm (8000D), 3nm (2000D) 


III. Nanofiltration Desalination System (BONA-GM-1818H) 


Product Specifications: 

◆ Minimum circulation volume: 8L; 

◆ Material tank: 48L; 

◆ Work pressure: 0 - 2.8 MPa; 

◆ Allowable operating temperature: 5 - 55℃; 

◆ Pump power: 3.75KW; 

◆ pH range of application: 2 - 12; 

◆ Filtration rate: 5 - 100 L/H; 

◆ Membrane element: One 150D nanofiltration membrane element; 

◆ Membrane element specification: 2.5' × 40' 

◆ Control method: Manual control, overpressure protection, overtemperature protection; 

◆ Power demand: Three-phase / 220V / 50Hz (It is recommended to reserve according to the factory standards); 

◆ Cleaning water: Softened water / purified water. Recommendation: SiO2 ≤ 10 ppm, Mn ≤ 0.02 ppm, Fe ≤ 0.05 ppm, pH = 6 - 8, Ca hardness ≤ 50 ppm; 

◆ Equipment dimensions: 1700 (length) * 700 (width) * 1250 (height) 

Product Features: 

1. Integrated equipment structure, equipped with rollers, and fast-installation towers at the inlet and outlet. 

2. Membrane Elements: Utilize imported membrane elements, which comply with FDA, USDA, and 3-A hygiene standards. 

3. The equipment is equipped with an automatic overpressure protection function, which will automatically shut down in case of overpressure; it also has an automatic overtemperature protection function, which will shut down the equipment in case of overtemperature. 

4. It can be equipped with other types of microfiltration, ultrafiltration, nanofiltration membrane or reverse osmosis membrane elements. 

5. All stainless steel welding is carried out using automatic argon gas protection, with single-sided welding and double-sided forming. The inner and outer surfaces of the pipeline have excellent quality. The operation is simple, the environment is clean and hygienic, and it is safe and reliable.


Basic configuration: 

Two multi-stage vertical centrifugal pumps, one SUS304 stainless steel membrane module, one membrane core; one shock-resistant pressure gauge, one temperature sensor, one pressure sensor, two flow meters, one pressure regulating valve, one jacketed material tank, one heat exchanger; equipment brackets, interlocking couplings, various pipes and their connecting components; one basic electrical control cabinet, one variable frequency start-up system.


Online consultation

Typical application fields

Food industry

Food industry

Clarification and concentration of beverages and juices; 

Fruit wine processing includes sterilization and clarification, as well as acid removal, etc. 

Dairy product production, sugar industry, soy sauce, 

The clarification of vinegar, etc.


Pharmaceuticals industry

Pharmaceuticals industry

Sterilization, extraction of pharmaceutical products, 

Separation, purification, concentration, desalination, 

Solvent replacement, etc.



Health care industry

Health care industry

Production of animal peptides and plant peptides; 

Health tea, coffee powder clarification and concentration; 

Vitamin separation, impurity removal from health tonics, etc.


The blood products industry

The blood products industry

Plasma protein concentration, antiviral immunoglobulin 

Protein purification, production of artificial blood;


Biotechnology industry

Biotechnology industry

Plant extract liquid concentration, natural pigment filtration concentration, honeysuckle impurity removal filtration, fermentation liquid concentration and refinement, enzyme preparation purification concentration, amino acid filtration concentration, etc.

Cosmetics industry

Cosmetics industry

Collagen grading, hyaluronic acid purification 

Production of plant essential oils, purification of natural pigments 

Purification of plant spices and removal of impurities for antioxidant properties.


Some using units

Some using units

Tsinghua University

Peking University

Beijing Institute of Technology

Fudan University

Zhejiang University

Go to Jiaotong University for school.

Xi'an Jiaotong University

Sichuan University

Sun Yat-Sen University

Nanjing University

University of Chinese Academy of Sciences

Northeast Normal University

Harbin Institute of Technology

Southeast University

Nankai University

Honghu City Xinhongye Food Co., Ltd.

Honghu City Jingli Aquatic Products and Food Co., Ltd.

Jinweihuang Co., Ltd.

Shenyang Sinochem New Materials Technology Co., Ltd.

Shandong Zhongke Henglian Bio-based Materials Co., Ltd.

Jilin Kale Ying Pharmaceutical Chemistry Co., Ltd.

Hebei Yuan Da Jiufu Biotechnology Co., Ltd.

Guangdong Yifang Pharmaceutical Co., Ltd.

Nanjing Vazyme Biotech Co., Ltd.

Shandong Xinhecheng Amino Acids Co., Ltd.

Xi'an Wanlong Pharmaceutical Co., Ltd.

Hunan Warner Pharmaceutical Factory Chiral Drug Co., Ltd.

Sichuan Meidaikang Huakang Pharmaceutical Co., Ltd.

Chongqing Kailin Pharmaceutical Co., Ltd.

Jingjing Pharmaceutical Co., Ltd.

Shandong Qidu Pharmaceutical Co., Ltd.

Wuhan Yeasen Biotechnology Co., Ltd.

Shanghai Coastal Technology Co., Ltd.

Shaanxi Bai Lu Pharmaceutical Co., Ltd.

Porton Fine Chemicals Ltd

Jingzhou Jingzhuang Mingzhu Food Co., Ltd.

Hubei Laker Food Technology Co., Ltd.

Shandong Asde Technology Co., Ltd.

Shandong Sinocera Functional Material Co.,Ltd

Quzhou Huayou Cobalt New Materials Co., Ltd.

Huaxi Biotechnology (Tianjin) Co., Ltd.

Shandong Bailongchuangyuan Biotechnology Co., Ltd.

Shandong Lihai Run Biotechnology Co., Ltd.

Jiangsu Chuangjian Medical Technology Co., Ltd.

Jiangsu Donghui Biotechnology Co., Ltd.

Texas Huoyang Biotechnology Co., Ltd.

Changzhou Yulan Biotechnology Co., Ltd.

Anhui Nu Jian Biotechnology Co., Ltd.

Baikai Sheng (Jiangsu) Biotechnology Co., Ltd.

Shandong Fuyang Biotechnology Co., Ltd.

Zhongke Guosheng (Hangzhou) Technology Co., Ltd.

Guangzhou Yuanmei Biotechnology Co., Ltd.

Zhejiang Xingyue Biotechnology Co., Ltd.

Shandong JiaoZhuo Furida Biotechnology Co., Ltd.

Suzhou TimeAlgae Pharmaceuticals Co., Ltd.

Qianjiang Liwu Aquatic Products and Food Co., Ltd.

Inner Mongolia Mengniu Dairy (Group) Co., Ltd.

Ya'an Bitu High-Tech Materials Co., Ltd.

Institute of Jiangxi Rare Earths, Chinese Academy of Sciences

Weifu High-Technology Group Co., Ltd

Bonner's technological advantages

Independently completed multiple domestic and international membrane equipment project engineering, with rich experience.

Independently completed multiple domestic and international membrane equipment project engineering, with rich experience.

We have a group of senior engineers specializing in membrane engineering applications, with many years of technical development and engineering practice experience.

We have a group of senior engineers specializing in membrane engineering applications, with many years of technical development and engineering practice experience.

We offer professional technical support and can provide on-site guidance for installation and commissioning.

We offer professional technical support and can provide on-site guidance for installation and commissioning.

A perfect customer service system and regular follow-up visits ensure the quality of the equipment.

A perfect customer service system and regular follow-up visits ensure the quality of the equipment.

The company has a service center that provides you with fast, efficient and cost-effective instrument repair services.

The company has a service center that provides you with fast, efficient and cost-effective instrument repair services.