Engineering case
The company is committed to providing innovative membrane material system solutions for various industries, which are widely used in the fields of gas and liquid separation and purification.
Fermentation of human-derived collagen for separation, purification, desalination and concentration
Protein desalination and concentration play a significant role in fields such as biological science, medical research, and food industry. The following is a detailed explanation of the functions of protein desalination and concentration:
Improve protein purity:
During the protein desalination process, through methods such as dialysis, the salt and other small molecule impurities in the protein solution can be removed, thereby improving the purity of the protein.
High-purity proteins are essential for many experiments and applications, such as drug development, biological analysis, and biotechnology.
Concentrated protein:
Protein concentration is the process of reducing the amount of water and other solvents in a solution and increasing the concentration of proteins.
The concentrated protein solution has significantly reduced in volume, making it easier to store, transport and use.
The commonly used protein concentration methods include ultrafiltration and freeze-drying, etc. These methods can effectively remove water while maintaining the biological activity of the proteins.
Regulate protein solubility:
Salt has a significant impact on the solubility of proteins. At low salt concentrations, the solubility of proteins increases as the salt concentration increases; when the salt concentration continues to rise, the solubility of proteins will decrease and may even precipitate.
By desalination, the salt concentration in the protein solution can be adjusted, thereby controlling the solubility of the protein and making it easier to separate and purify.
Maintain protein activity:
During the desalination and concentration processes, choosing appropriate methods and conditions can maximize the preservation of the biological activity of proteins.
For instance, ultrafiltration can rapidly filter solutions under mild conditions while effectively maintaining the activity of biological macromolecules; freeze-drying can directly remove water at low temperatures, reducing the risk of protein denaturation.
Improve the efficiency of experiments:
By desalination and concentration, the volume of the protein solution required for the experiment can be reduced, thereby speeding up the experimental process.
Meanwhile, high-purity and high-concentration protein solutions can enhance the accuracy and reliability of experimental results.
Reduce experimental costs:
The volume of the concentrated protein solution decreases, thereby reducing the costs of storage and transportation.
Meanwhile, high-purity proteins can reduce waste in experiments and the need for repeated experiments, thereby lowering the cost of the experiments.
In conclusion, protein desalination and concentration play a significant role in enhancing protein purity, concentrating proteins, regulating protein solubility, maintaining protein activity, improving experimental efficiency, and reducing experimental costs.
For many years, Wuhan Bona has been dedicated to the application process development of membrane separation technology. By integrating processes, membranes and equipment, it has accumulated rich experience in product purification and engineering-scale expansion. It not only solves manufacturing challenges but also improves product quality, and together with customers, it enhances the technical level of the industry.
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